Prevalence of pulmonary thromboembolism And associated Factors In clinically suspected Adult patients in SPHMMC From September 2021 to September 2023 Using chest CT angiography , Addis Abeba, Ethiopia

Abstract

ABSTRACT Background: Pulmonary thromboembolism is a condition that occurs when a blood clot that forms in a vein, loose and travels through the bloodstream to the lungs. It is a significant cause of morbidity and mortality of patients. To my knowledge and experience, there are only a few studies are done on the prevalence of pulmonary embolism and associated factors particularly in our country, Ethiopia and detailed study of it, aids in early patient management and prevention of it. Objective: The primary aim of this study is to determine the prevalence of pulmonary thromboembolism and associated factors among clinically suspected patients by chest computed tomography angiography at St. Paulo’s millennium medical college, Ethiopia. Methods: Facility-based cross-sectional study was conducted at St. Paulo’s millennium medical college, from September 2021 to September 2023.About 191 patients were taken by random sampling method. Sampling: The data was collected from patient card registry using questioner and from radiologic information system. Then, the data was exported and analyzed by using SPSS 25.Descriptive statistics were done to determine the prevalence of PTE among clinically suspected adults and binary logistic regression analysis was performed to identify possible factors. Hosmer-Lemeshow goodness of fit test was used to check the model. Finally, independent predictor variables of PTE were identified based on adjusted OR (AOR) with 95% CI and a p value of 0.05. Results: The prevalence of PTE among clinically suspected adults were 22%. The odds of PTE in patients with an underlying malignancy was 1.69 times (AOR=1.69, CI [1.22,11.58]) than those without an underlying active malignancy, the odds of PTE in female patients was 0.2times (AOR=0.268, CI [0.097,0.739]) than males and the odds of PTE in immobilized patients was 4.6 times (AOR=4.602, CI [1.77,11.91]). Conclusion and recommendation: This study found a significant correlation between PTE and female sex, immobility, and an active underlying malignancy and higher prevalence of PTE in our setup .Therefore, it would be best for health care professionals and concerned organizations to address the above risk factors for prevention of the disease. Keywords: - Prevalence, SPHMMC, associated factors, Pulmonary thromboembolism (PTE)