NON-ADHERENCE TO ANTI-TUBERCULOSIS TREATMENT AND ASSOCIATED FACTORS IN AKAKI KALITY SUBCITY, ADDIS ABABA, ETHIOPIA, 2017

Abstract

SUMMERRY Back ground: Non-adherence to anti-TB treatment may result in the emergence of multidrug resistant tuberculosis bacilli, prolonged infectiousness and poor TB treatment outcomes. The present study is intended to contribute to bridging the information gap, adequate knowledge & understanding barrier to adherence, understanding barrier to adherence and further reinforces the absolute necessity of helping TB patients that do not miss any doses of anti TB in Akaki kality sub city. Objective: The aim of this study is to assess the level of non-adherence to tuberculosis bacilli treatment and associated factors among adult TB Patients who attend in public health centre in Akaki Kality, Addis Ababa, Ethiopia 2017. Method: A facility based cross –sectional study design was conducted among adult tuberculosis patients who were following ant tuberculosis treatment in health centers of Akaki kality sub city from October 22 – December 8/2017. Data were collected by trained data collectors using a structured and pre-tested questionnaire. The sample size was 268 & selected by systematic random sampling method. Data were entered to EPI.Inf.7 and analyzed using SPSS ver. 20. Multiple logistic regressions were fitted to identify potential predictor and to control potential confounding variables. Odds ratio (OR) with 95% confidence interval was presented and p-value < 0.05 were considered statistically significant. Results: A total of 268 tuberculosis patients were interviewed; 57.1% were males and the overall non adherence for the last four days, seven days and the last 30 days before the survey were (11%, 13.8%, and17.9%,) respectively. Non-adherence to anti-TB medication were significantly associated such as Anti TB drugs side effect (AOR: 1.27 95% CI 1.107-3.80), OIs other than TB diseases (AOR: 6.43 95% CI 1.33-31.1), Urine discoloration(AOR:8.5 95% CI 1.92-9.67), ART drugs taken (AOR:3.01 95% CI1.45 5.35), Pyridoxine drugs taken(AOR: 3.9 95% CI 1.66-9.19)and continuation phase of chemotherapy (AOR: 2.8 95% CI 1.39-5.39) Conclusions: Non-adherence to anti-TB treatment due to, Anti-TB drugs side effect, OIs other than TB diseases, having Urine discoloration, TB/HIV co-infected, Pyridoxine drugs and continuation phase of chemotherapy were significantly associated with non-adherence to anti-TB treatment. Recommendation: Special attention on adherence counseling should be given to symptomatic patients, TB/HIV co-infected patients, and those in the continuation phase of the tuberculosis therapy. Key words: Non- Adherence, TB, AkakiKality sub city, Addis Ababa, Ethiopia