CD4 LEVEL AND POSTOPERATIVE OUTCOME OF RVI PATIENTS: A THREE YEAR CASE CONTROL STUDY

Abstract

Abstract INTRODUCTION HIV/AIDS continued to be global public health burden. The WHO 2016 report indicates worldwide prevalence of the disease is 36.7 million of which 19.4 million are found in eastern and southern Africa. It was a major challenge for surgeons for years with significant post-operative morbidity and mortality. OBJECTIVE The objective of this study is to determine the association between CD4 level of RVI patients and post-operative outcome following surgeries in St. Paul hospital millennium medical college. METHEDOLOGY A retrospective case control study of all RVI patients who were operated in the past three years in SPHMMC. RESULTS 47 HIV positive patients and 60 HIV negative patients of comparable age, sex and procedure were involved in the study. Overall postoperative complications and hospital stay were significantly increased in patients with low CD4 and operated on emergency bases. Complications were also increased in patients whose HIV status is known recently. No significant association found based on age and sex of the patients. There is no significant change in mortality. CONCLUSSION There is statistically significant association found between CD4 level and postoperative complications and hospital stay of RVI patients.