Histopathologic Patterns of Soft Tissue Tumors in St. Paul Hospital Millennium Medical College From first of January, 2014- December, 31, 2020 G.C.

Abstract

Abstract Background: Soft tissue tumors are a complex group of neoplasms with differentiation towards mesenchymaltissue occurring in all age groups. Although pathologically diverse, they frequently exhibit similar clinical presentations and radiological features. Therefore, correct histopathologic diagnosis is crucial [1, 2]. Despite histopathologic diagnosis is widely practiced in study area, no study was found on histopathologic pattern of soft tissue tumors. Therefore, this study was aimed to describe histopathology pattern of soft tissue tumors in Saint Paul hospital millennium medical college. Materials and methods: A cross sectional study design was employed on six years patient’s biopsy record of Saint Paul hospital millennium medical college from first of January, 2014- 31, December, 2020. Structured check lists was used to collect data. Data were entered into MS Excel and exported to SPSS V.28 for analyses. Data was described using frequency, proportions and median. Finally result was presented using tables, figures and narrative form. Results: A total of 449 patients were diagnosed with soft tissue tumor over the last six years with malignant to benign ratio of 1:4.7 and sex ratio of Male to Female 1.03:1. The age group at which soft tissue tumors commonly occur was from 21-30 (21.6%) years of age. The most favored site of occurrence (30.1%) was the lower limb. From the different histologic subtypes of sarcoma, the top three were Liposarcoma 18(24.3%), followed by undifferentiated pleomorphic sarcoma 15 (20.3%), which are common in adults and Rhabdomyosarcoma 9 (12.2%) which is common in youngsters. Conclusion:Benign tumors are five times more common than malignant. The most common soft tissue sarcoma in children is Rhabdomyosarcoma and in adults Liposarcoma and larger scale study needs to be planned to look at more aspects that could possibly contribute to the causes of soft tissue tumors. Keywords: Histopathology; Patterns; Soft tissue tumor; Sarcoma.