Pattern Outcome of Shock in Pediatric Intensive Care Unit of St Paul Hospital Millennium Medical College

Abstract

ABSTRACT Background: Shock is a common life-threatening condition that is characterized by a state of circulatory insufficiency, that creates an imbalance between tissue oxygen delivery and consumption, resulting in end-organ dysfunction and potentially death. It is classified into four categories based on its underlying pathophysiology: cardiogenic, hypovolemic, obstructive, and distributive. The patterns, outcomes, and associated factors of shock in Ethiopian PICUs have not been well studied. This is particularly concerning given the high burden of shock in Ethiopia, where it accounts for a significant proportion of pediatric mortality. Moreover, Ethiopia has limited preventative and curative healthcare systems and resources, which may further contribute to the poor outcomes of shock. Objectives: the main objective of the study is to determine the pattern, outcome, and associated factors of shock at the Pediatric Intensive Care Unit of St Paul Millennium Medical College. Methed:A cross-sectional observational study was conducted at St Paul Millennium Medical College Pediatric Intensive Care Unit from October 30, 2022, to November 1, 2023. The study was focus on children aged 1-month post-delivery to 17 years with clinical diagnoses of shock. Patients were selected using a simple random sampling technique with a sample size of 178. Data was collected using a structured questionnaire from chart revision and analyzed using SPSS. Mainly quantitative data analysis was implemented, with additional qualitative analysis on the association between the outcome and management principles, as well as other related factors. Results: In this study, 97(58.8%): 95%CI [51.5, 66.7] of patients was survived with 70(42.4%) of them were transferred to wards and 68(41.2%) were died. Conclusion and Recommendations: The study highlights the high burden of septic shock and associated mortality in the PICU at SPHMMC, with septic shock contributing the highest number of admissions into the PICU. The mortality rate of PICU was higher than previous study. Early detection and the transfer of critical patients to the ICU to improve their outcomes, a continuing effort should be made to improve the quality of care through support focusing on hemodynamic support and mechanical ventilator use. Keywords: Pattern Outcome Pediatric Children Shock, Associated Factors PICU St Paul Millennium Medical College