INPATIENT CLINICAL OUTCOME OF ADULT CEREBRAL VENOUS THROMBOSIS PATIENTS IN SAINT PAUL’S HOSPITAL MILLENIUM MEDICAL COLLEGE AND ZEWDITU MEMORIAL HOSPITAL, ADDIS ABABA, ETHIOPIA: 5 YEARS REVIEW

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ABSTRACT Background Cerebral venous thrombosis is a relatively uncommon neurological disorder predominantly affecting women. It has a good outcome in most patients. Few patients may end up with permanent neurological deficits or even die if not managed early. CVT is under reported and not properly studied in our country. The main objective of this study is to assess the clinical presentation and inpatient outcome of adult patients diagnosed to have cerebral venous thrombosis in SPHMMC and ZMH over the past 5 years. Method A cross sectional retrospective chart review was conducted over 3 months from June 2022 up to august 2020 G.C at SPHMMC and ZMH on all patients who were admitted between September 2017 up to September 2021.Outcome was assessed in response to clinical presentation and inpatient outcome. Data was collected through chart review using a structured questionnaire. Collected data was analyzed using SPSS version 20. Frequency was used to summarize descriptive statistics of the data. Tables and figures were used for data presentation. Result The median age of patients was 28 years. Majority of the patients (76.3%) were female. The commonest presenting symptom was headache (97.4%) followed by motor weakness (47.4%) and visual impairment (42.1%). Majority of the patients (57.9%) had symptoms lasting less than 2 weeks. About 52.6% of patients were found to be either pregnant or in the peurperium period. All of the studied patients received an anticoagulation medication. The inpatient outcome of the patients was good in general with majority of the patients (71%) having a complete recovery at discharge. Conclusion Pregnancy / peurperium was found in more than half of the patients in this study. Attention should be given to the diagnosis of CVT in pregnant/ post partum females who present with signs and symptoms of this illness. Multidisciplinary approach should be practiced in the diagnosis of these patients by actively including the obstetricians.

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