MRI Measurement of Endometrial Thickness in Postmenopausal Patients in Saint Paul’s Hospital Millennium Medical College.

Abstract

Summary Background: Female gynecologic conditions arising from the endometrium are common and depend on a women’s age, her menstrual history, and use of medications such as hormone replacement. The accepted normal endometrial thickness is 5mm; lesions with endometrial thickness <5mm are considered benign, whilst those >5mm usually are considered malignant. However, recent studies suggest that asymptomatic endometrial thickness of even 8-11mm in postmenopausal women may be normal. (1) Objective: The objective of the study is to assess the normal endometrial thickness range in postmenopausal patients imaged in St Paul’s Hospital Millennium Medical College by Magnetic resonance imaging T2-weighted sagittal images retrospectively as measured by a single radiologist. Methodology: A retrospective cross sectional study will be employed and data will be collected from the image pool of the Radiology department of St Paul’s Hospital Millennium Medical College. The medical records for the purpose of this study will be selected by convenience sampling, a type of non-probability sampling method. with total sample size of 97. Collected data will be cleaned, edited and entered using Epi-Data version 3.1 into a computer and analyzed by SPSS version-25. Work plan and budget: The study will be conducted from April 1, 2019 to August 15, 2019.The estimated budget will be 26,950 ETB and source of funding will be from St Paul’s Hospital Millennium Medical College.