PREVALENCE AND ASSOCIATED FACTORS WITH THE DEVELOPMENT OF PRESSURE ULCER IN ADULT INTENSIVE CARE AND HIGH DEPENDENCY UNIT AT SAINT PAUL`S HOSPITAL MILLENIUM MEDICAL COLLEGE
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Abstract
Abstract
Background: Pressure ulcer is a localized area of damage to the skin and/or underlying tissue,
usually over a bony prominence, resulting from sustained pressure or pressure in combination with
shear, as defined by the European Pressure Ulcer Advisory Panel (EPUAP). It is a largely
preventable but serious health problem in both acute and chronic healthcare settings. Pressure
ulcers impose a significant burden on patients, caregivers, and healthcare systems by increasing
morbidity, mortality, length of hospital stay, and healthcare costs. Although pressure ulcer
development is considered an indicator of quality of care, concerns remain regarding
circumstances in which they may be unavoidable. Understanding the magnitude of the problem
and identifying associated risk factors are essential for effective prevention.
Objective: the prevalence and associated risk factors for the development of pressure ulcers at
critical care settings (intensive care units and high dependency units) of Saint Paul's Hospital
Millennium Medical College was assessed.
Methods: An institution-based cross-sectional study was conducted at Saint Paul’s Hospital
Millennium Medical College from September 2025 to January 2026. Data was collected using an
interviewer-administered structured questionnaire and observational checklist. Data has been
entered into and analyzed using appropriate statistical software. Binary logistic regression analysis
was performed to identify factors associated with pressure ulcer development. Variables with a p
value ≤ 0.25 in the bi-variable analysis were entered into multivariate logistic regression. Variables
with a p-value < 0.05 at a 95% confidence interval is considered statistically significant. The
Findings are presented using text, tables, and graphs.
Results: The prevalence of pressure ulcers was 12.5% (28/224; 95% CI: 8.5–17.6%), with the sacra
l area being the most commonly affected site (10.3%). Grade 1 ulcers were most frequent (6.3%).
Independent predictors of pressure ulcer development included smoking (AOR = 202.96, 95% CI:
4.70–8764.32, p = 0.006), incontinence (AOR = 0.001, 95% CI: 0.000–0.22, p = 0.012),
repositioning every 4 hours compared to every 2 hours (AOR = 110.29, 95% CI: 3.14–3874.07, p
= 0.010), impaired level of consciousness (AOR = 0.27, 95% CI: 0.12–0.61, p = 0.002), and longer
hospital stay (AOR = 2.67 per day, 95% CI: 1.61–4.43, p < 0.001). Age, BMI, sex, and Branden
risk levels showed marginal associations but were not statistically significant after adjustment. The
multivariate model showed excellent fit (Hosmer-Lemeshow χ² = 0.721, Df = 8, p = 0.999) and
classified 96.9% of cases correctly.
Conclusion: Pressure ulcers remain a significant concern among hospitalized patients at Saint
Paul’s Hospital. Major risk factors included smoking, incontinence, less frequent repositioning,
impaired consciousness, and prolonged hospitalization. Preventive strategies, including early risk
assessment, frequent repositioning, and careful monitoring of high-risk patients, are essential to
reduce the burden of pressure ulcers in hospital settings.
Keywords: Pressure ulcer, prevalence, risk factors, cross-sectional study, quality of care