ASSESSMENT OF HEALTH-RELATED QUALITY OF LIFE AMONG HYPERTHYROID PATIENTS TREATED WITH ANTI-THYROID DRUGS AND DEFINITIVE MANAGEMENT, CROSS-SECTIONAL STUDY

Abstract

ABSTRACT Background: The purpose of treating hyperthyroidism is to reverse or preserve thyroid function, prevent recurrent disease, relieve symptoms and improve quality of life. Symptoms often may persist for a long time following euthyroidism, with long-term quality of life impairments. Objective: This study assessed disease-specific quality of life in patients with hyperthyroidism treated with Anti-thyroid drugs and definitive management. Methodology: Institutional-based cross-sectional study design applied with simple random sampling technique used to recruit 240 Patients. Self-administered ThyPRO Questionnaire used for data collection and analysis done with SPSS software version 27.0.1. Result: The median age of the participant is 40 years with interquartile range of 32 to 50 years. 84.6% of the participants are females. 67.9% of patients had Toxic multi-nodular goiter as cause of hyperthyroidism and 73.5% of study participants were treated with anti-thyroid drugs, the rest with thyroidectomy. Overall quality of life significantly affected in patients treated with Anti-thyroid drugs than Thyroidectomy. Despite that more than half of participants recommended ATD for their loved ones if they had to advise them. Conclusion: Hyperthyroidism is more prevalent in younger adults and females. Patients treated with anti-thyroid drug have less overall quality of life than those who had thyroidectomy. KEY WORDS: Ant-thyroid drug; Graves ‘disease; Quality of life; Hyperthyroidism; Thyroidectomy; ThyPRO; Toxic nodular goiter