PREVALENCE AND MANAGEMENT OUTCOME OF OVARIAN CANCER IN GYNECOLOGY WARD ADMITTED PATIENTS FROM 2003E.C TO 2005 E.C IN St PAULS HOSPITAL MILLENNIUM MEDICAL COLLEGE, ADDIS ABEBA, RETROSPECTIVE STUDY

Abstract

ABSTRACT BACKGROUND: Ovarian cancer is a commonly diagnosed and particularly deadly gynecologic malignancy worldwide. This study aimed to assess the prevalence and management outcome of ovarian cancer in 5 years period in SPHMMC gynecology ward. METHODS: A retrospective study from patients’ individual cards was implemented to review the prevalence and management of ovarian cancer in the past 5years in SPHMMC (from Meskerm 2003 to Nehasse 2007E.C.) RESULT: Out of 125 patients cards reviewed, there were 64 patients with malignant ovarian cancer. The mean age (SD) was 44.25years (16) and the commonest age group was 45-54 years which is at early age as compare to other studies. Nulliparty was being the only major risk factor identified in this study (31.2%). More than half of patients were symptomatic before the diagnosis of the cancer for less than 6 months. These patients commonly presented with abdominal swelling, abdominal pain and weight loss. Most patients were stage 3 (25%) and stage 4 (54.7%) disease. For 43.8% of patients, surgeries were done, 32.8% were managed with surgery then chemotherapy and 9.4% were admitted to ward with no further management. Epithelial ovarian cancer was the commonest histology type (45.3%). Half of the patients were lost from follow up. CONCLUSION AND RECOMMENDATION: There is emerging pattern of ovarian cancer at younger age and by far involves parous woman. Most patients presented at advanced stage and significant number of patients lost from follow-up. Population based studies are required to determine the risk factors in our set up.