PREVALENCE AND ASSOCIATED FACTORS OF CHRONIC KIDNEY DISEASE AMONG DIABETICS PATIENT THAT ATTENDED ST PAUL’S HOSPITAL MILLENIUM MEDICAL COLLEGE

Abstract

Abstract Background: Patients with diabetes mellitus are at an increased risk of developing chronic kidney disease (CKD).Patients with diabetes and chronic kidney disease; have a lower quality of life and higher health care costs, face the prospect of end-stage renal disease requiring dialysis, and more importantly, they have an extremely elevated cardiovascular risk and correspondingly reduced survival. In association with the increasing prevalence of diabetes and its chronic complications, the burden of chronic kidney disease and the associated risk factors among patients with diabetes mellitus in Ethiopia is unknown. Objectives: The objective of this study is to determine the prevalence of chronic kidney disease and the associated risk factors among adult diabetes mellitus patients attending the diabetes clinic of St Paul Specialized Hospital, in Addis Ababa Ethiopia. Methods: A hospital based cross sectional study will be conducted among 306 diabetes mellitus patients aged ≥19 years; during the period of March 2017 to July 2017. All necessary socio demographic and risk factor information’s will be collected using structured formats. The estimated glomerular filtration rate (eGFR) for CKD; will be determined using the abbreviated MDRD equation from serum creatinine. Results: 71(23.7%) of the study participants were found to have CKD, as defined by eGFR < 60 ml/min/1.73 m2, according to the MDRD equations. Significant risk factors for CKD in the study subjects were older age, longer duration of diabetes and the presence of hypertension with (P < 0.001). Conclusion:CKD was present in about 23.7% diabetic adults attending the follow up clinic at St Paul hospital, in Addis Ababa Ethiopia. Risk factors for CKD were similar to those reported in developed country studies. Recommendation: This study proposes that a large scale study to be conducted encompassing a large number of diabetic populations to find out the prevalence of CKD and its associated factors so that a preventive strategy implemented or designed to reduce the expansion of the disease. Keywords: Chronic Kidney Disease, Diabetes, Risk Factors, Estimated Glomerular Filtration Rate